Postdoctoral Research Fellow in Transcriptional/Epigenetic Regulation of Aging @ Karolinska Institutet
Position : Postdoctoral Research Fellow
Research group and project :
- Two postdoctoral positions are available in the laboratory of Christian Riedel at the KI/AZ Integrated Cardio Metabolic Centre (ICMC). The research group studies the molecular mechanisms that regulate aging and age-related disease. Focus of these fully funded positions is to investigate aging-regulatory signaling pathways and their downstream transcription regulatory events, with a particular interest in aging-regulatory transcription factors, their fundamental mechanisms of action, and how they synergize with cofactors and the chromatin landscape in the regulation of stress-resistance and longevity promoting genes.
- Our research uses diverse model systems, most importantly the nematode C. Elegans and mammalian tissue culture, and combines Biochemistry (e.g. proteomics), cytology, and high-throughput sequencing techniques (e.g. ChIP-Seq and mRNA-Seq) with high-throughput genetic screening approaches (RNAi), to understand the regulation of aging at molecular and mechanistic resolution.
Duties : The postdoctoral fellows are expected to play a leading role in experimental design, experimentation, analysis, and the presentation/publication of results.
Qualifications/Entry requirements :
- The applicants should have a PhD degree in molecular biology, Biochemistry, Molecular Genetics, Physiology, or similar. They are expected to be a talented, highly motivated, and hardworking researchers, with a good understanding of biochemical, molecular biology, and genetic techniques. Applicants with backgrounds in transcriptional regulation, epigenetics, aging biology, or endocrine signaling, as well as prior experience with either C. elegans or tissue culture systems are particularly encouraged to apply. Also prior experience in next generation sequencing methodologies or proteomics will be appreciated. Strong emphasis will be placed on the applicants’ scientific track-record, in particular peer-reviewed publications.
- All applicants should have good communication skills and be proficient in spoken and written English.
- A person is eligible for a position as postdoctoral research fellow, only if he/she has obtained a PhD no more than seven years before the last date of this postdoc employment.
Application process :
-
A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic
positions, academic title, current position, academic distinctions, and committee work
- A complete list of publications
- A summary of current work (no more than one page)
- Verifications for crediting of illness, military service, work for labour unions or student organisations, parental leave or similar circumstances
- Verification from the thesis defence committee or the equivalent (only if the thesis defence is scheduled within three months after the application deadline)
Deadline : 25.05.15
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