PhD student position in "role of microbiotia in chemotherapy induced mucositis" at University Medical Center Groningen
Working Environment :
- This research project is a dual project between the University Medical Center Groningen (UMCG) and Nutricia Research at the departments of Paediatric Oncology, Paediatric Gastroenterology en Medical Microbiology (www.mmb-umcg.nl) of the UMCG and the laboratory of Nutricia Research in Utrecht (www.nutriciaresearch.com).
- Working at the University Medical Center Groningen means working at the frontiers of knowledge. The Faculty of Medical Sciences offers researchers and students the opportunity to expand those frontiers, to develop their talents and together with others realize top quality achievements. The Pediatric Oncology Research Group is embedded in the program of the Northern Netherlands Oncology Center and collaborates with various (inter)national partners.
- Nutricia Research is the global research and innovation organisation behind the Early Life Nutrition and Advanced Medical Nutrition divisions of Danone and located in the Utrecht Science Park in the Netherlands. Nutricia Research develops products for people with specific nutritional needs, such as those with malnutrition, allergies, muscle loss and other specific disease conditions. Nutricia Research has 1200 employees world-wide and 150 of them have PhD degrees. Our efforts are directed toward one goal: bringing health through food to as many people as possible. This is the foundation of our research and innovation.
Job Description :
- The long term cancer-free survival of pediatric cancer patients has significantly increased during the past decades due to more intensive chemotherapy treatment regimens. However, more intensive treatment has also resulted in serious morbidity and even mortality. One of the side-effects is mucosal damage (i.e. mucositis) in the gastro-intestinal tract, thereby loosing the epithelium necessary for the normal functions of the GI-tract. There are strong indications that there is a relationship between the microbial flora of the gut and mucositis.
- In this research project we will study this relationship and try to develop interventions to decrease the duration and / or severity of the mucositis.
- The studies will be done in vitro, and by using an animal model of chemotherapy-induced mucositis. The in vitro studies will be done mainly in the laboratory of Nutricia Research in Utrecht, the animal studies mainly in the UMCG.
- The results will be published in scientific journals. After 4 years a thesis must be written and a Ph.D. degree should be obtained.
What do we need :
- Masters degree in biology or biomedical sciences
- Motivated, enthusiastic and research-driven
- Flexible and accurate
- Willing to work with experimental animal models
- Good social and communicative skills
What we offer :
- Your salary is € 2.200,- gross per month in the first year up to a maximum of € 2.818,- gross per month in the last year (scale PhD).
- In addition, the UMCG will offer you 8% holiday pay, an 8.3% end-of-year bonus and a personal development budget.
- The terms of employment comply with the Collective Labour Agreement for Medical Centers (CAO-UMC).
- Duration of the contract: four years
- Maximum hours per week: 36
Deadline : 11.01.15
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