Postdoc in Quantitative Physiology of Glycerol Utilising Yeasts at Department of Systems Biology,Denmark Technical University
The position is open within the Section for Eukaryotic Biotechnology, one of 5 research sections at the Department of Systems Biology.
- Description : The Section for Eukaryotic Biotechnology is dedicated to the exploitation of biodiversity as a source of new compounds and, through understanding Cell Biology and physiology, use systems and synthetic biology to design advanced cell factories. The profile of the section comprises research groups with competences in mycology, molecular biology, metabolomics, Bioinformatics and fermentation technology.
- Note : The project is funded by the ERA-Industrial Biotechnology Project IPCRES (Integrated Process and Cell Refactoring Systems for Enhanced Industrial Biotechnology). The project comprises 8 academic and industrial partners from Denmark, Germany, Spain, Portugal, UK and The Netherlands. The aim of the project is to port pathways into yeasts for the production of value added compounds from glycerol. Genetically engineered yeasts will be characterised with high throughput micro-scale process techniques and at lab scale. Transcriptomic and metabolomic data will be combined with process insights to dictate refactoring of both pathways and host cell factories. These steps will be repeated for second-iteration cells, driving better performance.
- Responsibilities and tasks : The successful candidate will work within the group Fungal Physiology and Biotechnology who have an overall commitment to the exploitation of biodiversity of fungi, their utilization in basic research as well as applications in Biotechnology. The candidate will integrate closely with other scientists in the group and across the section, with backgrounds in molecular biology, fermentation technology and Bioinformatics. The day-to-day work will be performed in close collaboration, the group leader, one postdoc and one PhD student who form the IPCRES project team at DTU.
Qualifications :
- Candidates should have a PhD degree or equivalent and the candidate must have
- A theoretical background in fungal physiology
- A strong practical background in submerged cultivation of yeast, both at micro- and lab-scale with batch and continuous modes of cultivation
- Considerable practical experience with controlled and automated lab-scale fermenters
- Experience with data handling and quantitative physiology of yeasts
- Experience with sample handling and preparation for metabolomics and transcriptomics
- Good writing and communication skills
The candidate should preferably have :
- Experience of 13C labelled metabolic flux analysis
- Sound knowledge of systems biology tools and techniques
- Experience in supervising and teaching students
It is expected that the successful candidate can :
- Co-ordinate and collaborate with a multi-disciplinary team
- Work independently and assist in management of the research activities within the group
- Design and implement experimental strategies
- Participate actively in project meetings and communicate own research results
- Participate actively in defining project strategy and group activities
Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach all your materials in English in one PDF file. The file must include:
- Application (cover letter)
- CV
- Diploma
- List of publications
Deadline : 09.12.14
APPLY ONLINE
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